The Effect of Chicory on Bilirubin Level in Newborns Suffering From Jaundice: A Systematic Review

Background: Jaundice is the most prevalent reason for infants’ hospitalization during their first month of birth, and herbal medicine has long been used alongside phototherapy to treat this problem. Objectives: The present systematic review investigates chicory’s influence on bilirubin levels in infants with jaundice. Methods: In study, Iranian databases, including Barekat Gostar, Scientific Information Database (SID), Irandoc, Magiran, along international Cochrane Library, Web Science, Scopus, PubMed, Google Scholar search engines were explored relevant keywords retrieve pertinent studies. Results: Among 7 selected articles a sample size 408 (204 people intervention group 204 control group) from 2006 2020, 4 studies vitro 3 randomized clinical trials. these studies, mothers’ pregnancy duration ranged between 30.9 38.8 weeks, age days, weight 1544 3316 g. Although chicory administration varied across reported its effectiveness reducing bilirubin, whereas other no effect infants. Conclusions: Iran was only country that evaluated neonatal jaundice form several research However, due limited number different dosages chicory, way consuming type babies, we could not reach general conclusion efficacy chicory.